Vim li cas cov me nyuam tsis tau txais Covid phem? Cov kws tshawb fawb tab tom pib nkag siab

LONDON - Ib qho kev paub tsis meej nyob ntev ntawm Covid-19 kev kis thoob ntiaj teb, kev noj qab haus huv thoob ntiaj teb uas tau ua rau ntau dua 6 lab tus neeg tuag, yog cov menyuam yaus tau dim los ntawm tus kabmob - feem ntau - thiab tsis tau ntsib qhov twg ze qhov hnyav. ntawm cov mob uas cov neeg laus muaj.

Thaum Covid tau tshwm sim thaum lig 2019 thiab pib kis thoob ntiaj teb, cov kws tshawb fawb tau nkag siab txog tus kab mob no thiab yuav ua li cas los tawm tsam nws, nrog cov tsev kho mob sim sib txawv cov txheej txheem los cawm cov neeg mob phem tshaj plaws hauv cov tsev kho mob hnyav.

Kev hlub tshua, ob peb ntawm cov neeg mob no yog menyuam yaus, ua rau muaj kev paub tsis meej rau cov kws paub txog kev noj qab haus huv rau pej xeem vim li cas cov menyuam yaus tsis mob hnyav lossis tuag nrog Covid.

Cov kws tshawb fawb tseem muaj kev ntxhov siab me ntsis txog vim li cas cov menyuam yaus tsis cuam tshuam los ntawm Covid, txawm hais tias kev tshawb fawb tau maj mam ua kom pom tseeb tias yuav ua li cas, thiab vim li cas, cov me nyuam cov lus teb rau Covid txawv ntawm cov neeg laus.

"Ib tug lej ntawm cov kev xav tau raug qhia, suav nrog kev siv tshuaj tiv thaiv kab mob hauv lub cev zoo dua, tsis tshua muaj kev pheej hmoo ntawm kev tiv thaiv kab mob ntau dhau raws li tshwm sim hauv Covid hnyav, tsawg dua hauv qab co-morbidities thiab tej zaum yuav tsawg dua ACE-2 receptors nyob rau hauv lub ntsws sab sauv epithelium - tus receptor. rau qhov uas SARS-CoV-2 [Covid] khi, "Dr. Andrew Freedman, tus kws qhia ntawv ntawm cov kab mob sib kis ntawm UK's Cardiff University Medical School, hais rau CNBC hauv emailed lus, ntxiv tias txawm li cas los xij qhov tshwm sim tsis tau "tau nkag siab tag nrho."

Nws tau sau tseg tias yuav tsum muaj kev tshawb fawb ntxiv ua ntej peb muaj cov lus teb meej tab sis lub cev ntawm cov pov thawj tau tshwm sim qhia tias Covid ua rau muaj kev pheej hmoo tsawg dua rau cov menyuam yaus, thiab vim li cas qhov ntawd yuav yog.

Nws tau nkag siab tias qhov kev pheej hmoo ua rau cov neeg laus los ntawm Covid nce nrog lub hnub nyoog raws li peb lub cev tiv thaiv kab mob ua rau qeeb qeeb, thiab tsis muaj txiaj ntsig zoo ntawm kev sib ntaus sib tua, kis kab mob.

Tshwj xeeb, qhov kev pheej hmoo yuav nce ntxiv rau cov neeg hauv lawv cov 50s thiab nce ntxiv rau cov neeg hauv lawv cov 60s, 70s, thiab 80s, Lub Chaw Tiv Thaiv Kab Mob thiab Tiv Thaiv tau hais tias, nrog cov neeg muaj hnub nyoog 85 thiab laus dua, feem ntau yuav mob heev. Muaj tej yam mob hauv qab no kuj tuaj yeem ua rau cov neeg laus mob hnyav dua.

Muaj ntau qhov kev tshawb fawb tsis ntev los no saib qhov sib txawv ntawm cov neeg laus lub cev tiv thaiv kab mob rau Covid, thiab cov menyuam yaus, thiab cov no tau pom qhov sib txawv ntawm ob qho tib si nrog cov tom kawg muaj qhov muaj zog dua thiab "innate" tiv thaiv kab mob.

Kev tshawb fawb ua los ntawm Wellcome Sanger Institute thiab University College London, thiab luam tawm nyob rau hauv Ntuj phau ntawv journal nyob rau lub Kaum Ob Hlis, pom muaj zog "innate" lub cev tiv thaiv kab mob nyob rau hauv cov hlab cua ntawm cov me nyuam, tus cwj pwm los ntawm kev xa tawm sai ntawm interferons - uas tau tso tawm nyob rau hauv lub xub ntiag ntawm tus kab mob los yog kab mob hem thiab pab txwv tsis pub kis kab mob thaum ntxov - UCL hais.

Lub sijhawm no hauv cov neeg laus, cov kws tshawb fawb pom tias muaj kev tiv thaiv kab mob tsawg dua uas txhais tau hais tias tus kab mob "muaj peev xwm ua tau zoo dua tuaj yeem nkag mus rau lwm qhov ntawm lub cev uas tus kab mob nyuaj rau tswj."

Kristin Mondy, tus thawj coj ntawm cov kab mob sib kis ntawm Dell Tsev Kawm Ntawv Kho Mob ntawm University of Texas, hais rau CNBC tias "tawm ntawm ntau qhov kev xav uas tam sim no nthuav tawm hauv cov ntaub ntawv, cov pov thawj zoo tshaj plaws rau hnub no txhawb nqa qhov kev xav thiab kev tshawb pom tias cov menyuam yaus muaj zog dua. Innate tiv thaiv kab mob piv rau cov neeg laus, tshwj xeeb tshaj yog nyob rau hauv lub qhov ntswg mucosal cov ntaub so ntswg uas lub cev tiv thaiv kab mob tuaj yeem tswj tau sai dua thiab tshem tawm tus kab mob piv rau cov neeg laus. "

"Qhov tau hais tias, peb kuj paub tias cov menyuam yaus muaj kev cuam tshuam ntau dua (tshaj li cov neeg laus) rau Multisystem Inflammatory Syndrome uas yog lub cev tiv thaiv kab mob ntau dhau rau Covid-19, ua rau feem ntau ua rau mob ntau dhau ntawm cov kabmob uas tsis yog lub ntsws (feem ntau lub plawv / hlab ntsha. system thiab gastrointestinal ib ntsuj av).

Lwm qhov zoo ntawm cov menyuam yaus muaj yog lawv kis tau tus kab mob ntau dua, tshwj xeeb tshaj yog nyob rau lub sijhawm uas cov kab mob tuaj yeem kis tau yooj yim ntawm cov menyuam hauv tsev kawm ntawv. Cov menyuam yaus feem ntau kis tau tus kab mob no yog mob khaub thuas tsis zoo thiab cov no feem ntau tshwm sim los ntawm ntau hom kab mob xws li rhinoviruses (qhov feem ntau ua rau mob khaub thuas) nrog rau cov kab mob ua pa syncytial (RSV) thiab tus mob coronaviruses.

Coronaviruses yog ib tsev neeg ntawm cov kab mob uas feem ntau ua rau mob me me mus rau nruab nrab cov kab mob ua pa sab saud hauv tib neeg tab sis ob peb, suav nrog Covid-19 thiab SARS thiab MERS, tau tshwm sim los ua kev hem thawj kev noj qab haus huv thoob ntiaj teb.

Ralf Reintjes, tus kws tshaj lij ntawm kev kis kabmob ntawm Hamburg University of Applied Sciences, tau piav qhia rau CNBC tias cov menyuam yaus lub cev tiv thaiv kab mob muaj ntau qhov zoo thaum nws los tawm tsam kev kis kabmob.

"Ua ntej tshaj plaws, lawv tseem hluas yog li lawv lub cev tiv thaiv kab mob tau sib tw ntau qhov twg los xij ... thaum lawv muaj ib xyoos lossis ob xyoos txog rau 10 lossis 12 xyoos, lawv dhau los ntawm ntau tus kab mob," Reintjes hais rau CNBC hnub Monday.

Nws tau hais tias "Lawv tau txais kev sib cuag nrog lwm tus kabmob coronaviruses lub sijhawm no yog li lawv lub cev tiv thaiv kab mob yog nyob rau hauv kev cob qhia, thiab tseem hluas heev thiab haum," nws hais ntxiv, thaum menyuam yaus lub cev tiv thaiv kab mob tau ntsib nrog Covid-19, muaj ntau heev. ntawm kev xyaum tawm tsam ntau yam kab mob thiab tus mob coronaviruses, lawv muaj lub zog tiv thaiv kab mob ntau dua li cov neeg laus uas nyiam kis tus kab mob tsawg dua.

Qhov tshwm sim tsis yog tshwj xeeb rau Covid-19 ib qho, Dr Andrew Freedman tau hais tias, nrog cov menyuam yaus feem ntau tuaj yeem tawm tsam lwm yam kabmob zoo dua li cov neeg laus, txawm hais tias tsis yog txhua qhov xwm txheej.

"Piv txwv li, cov menyuam yaus feem ntau tsis muaj cov tsos mob ntawm tus kab mob siab A thiab tus kab mob Epstein-Barr feem ntau asymptomatic nyob rau hauv cov menyuam yaus uas tsis zoo rau cov hluas thiab cov hluas uas muaj mob qog noj ntshav. Muaj, tau kawg, muaj lwm yam kab mob uas hnyav dua rau cov menyuam yaus piv rau cov laus thiab cov laus, xws li RSV [tus kab mob ua pa syncytial] thiab mob khaub thuas.

Kev tshawb fawb luam tawm thaum kawg 2021 saib rau tag nrho cov kev pheej hmoo kis tus kab mob rau cov menyuam yaus pom tias qhov no tsawg heev rau feem coob ntawm cov menyuam yaus thiab cov tub ntxhais hluas hnub nyoog qis dua 18 xyoo.

Txoj kev tshawb no, ua los ntawm cov kws tshawb fawb los ntawm ntau lub tsev kawm ntawv Askiv, tau kawm txog kev tuag ntawm cov menyuam yaus thiab cov tub ntxhais hluas hauv tebchaws Askiv txij lub Peb Hlis 2020 txog Lub Ob Hlis 2021 - thawj xyoo ntawm kev sib kis - sib txawv ntawm cov neeg tuag ntawm Covid thiab cov neeg tuag ntawm lwm qhov laj thawj. tab sis tau coincidentally kuaj pom tus kab mob.

Nws pom tias ntawm 3,105 tus menyuam yaus thiab cov tub ntxhais hluas uas tuag los ntawm txhua qhov ua rau thawj xyoo muaj kabmob kis thoob tebchaws Askiv, 25 tus neeg tuag los ntawm Covid, sib xws rau tag nrho cov neeg tuag ntawm 2 tus neeg tuag rau ib lab tus menyuam hauv tebchaws Askiv.

Ntawm 25 tus menyuam yaus uas tu siab tuag ntawm Covid, 19 muaj mob hauv qab kev noj qab haus huv, suav nrog qee tus menyuam yaus uas muaj ntau yam tsis zoo thiab lub neej txwv.

Thaum lwm tus menyuam yaus uas tuag tau tshwm sim tsis muaj mob hauv qab no, cov kws tshawb fawb tau ceeb toom tias tej zaum yuav muaj qhov tsis paub txog kev mob nkeeg lossis tsis muaj kev kuaj mob caj ces rau cov kab mob hnyav nrog Covid.

Thaum txoj kev tshawb fawb pom tias tag nrho cov kev pheej hmoo rau cov menyuam yaus yog "tsis tshua muaj" nws tau sau tseg tias cov neeg muaj hnub nyoog tshaj 10 xyoo, ntawm haiv neeg Esxias thiab Dub, thiab cov neeg uas muaj comorbidities (neurological mob yog cov feem ntau comorbidity) yog over-sawv cev nyob rau hauv lub cov ntaub ntawv kev tuag piv rau lwm cov menyuam yaus.

Txoj kev tshawb no xaus lus tias Covid "tsis tshua muaj neeg tuag" txawm tias ntawm cov menyuam yaus uas muaj kab mob hauv qab. Tseeb tiag, nyob rau hauv lub xyoo uas tau kawm, kwv yees li ntawm 469,982 tus menyuam yaus hauv tebchaws Askiv muaj Covid, txhais tau tias tus menyuam txoj kev muaj sia nyob tau pom tias muaj 99.995%.

Pediatric Covid cov ntaub ntawv thiab cov ntaub ntawv tuag los ntawm Teb Chaws Asmeskas qhia zoo ib yam li kev pheej hmoo tsawg rau cov menyuam yaus.

Tsoomfwv Meskas Lub Chaw Tiv Thaiv thiab Tiv Thaiv Kab Mob tau tshaj tawm lub lim tiam dhau los tias tag nrho 966,575 tus neeg tuag tau tshwm sim los ntawm Covid hauv Tebchaws Meskas thaum muaj kev sib kis. Nyob nruab nrab ntawm 2020 thiab 2022 muaj 921 tus neeg tuag ntawm 0-17 xyoo uas tau tshwm sim los ntawm Covid, tawm ntawm 73,508 tus neeg tuag hauv pawg hnub nyoog no uas tau tshwm sim los ntawm txhua qhov laj thawj.

Txij li thaum muaj kev sib kis tau pib, cov menyuam yaus tau suav txog 19% ntawm txhua tus neeg mob Covid hauv Asmeskas, raws li American Academy of Pediatrics 'cov ntaub ntawv tshaj tawm hauv lub xeev tau tshaj tawm lub lim tiam dhau los, tab sis lub tsev kawm ntawv tau hais tias "ntawm cov xeev tau tshaj tawm, cov menyuam yaus yog 0.00%-0.27% ntawm tag nrho Covid-19 tuag, thiab 3 lub xeev tau tshaj tawm tias tsis muaj menyuam tuag."

Cov menyuam yaus tseem sawv cev ib ncig ntawm ib feem tsib ntawm txhua qhov Covid; rau lub lim tiam xaus lub Peb Hlis 17, cov menyuam yaus suav txog 18.3% ntawm cov xwm txheej qhia txhua lub lim tiam. Cov menyuam yaus hnub nyoog qis dua 18 xyoo suav nrog 22.2% ntawm cov neeg Asmeskas.