Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tshuaj Khomob tus kws tshaj lij rau hnub Wednesday tau pom zoo pom zoo los ntawm lub khw muag khoom ntawm cov tshuaj tsuag qhov ntswg Narcan kom thim rov qab cov tshuaj opioid ntau dhau, uas yuav nthuav dav nkag mus rau kev kho lub neej.
Kev kub ceev BioSolutions' Narcan yog feem ntau muag kev kho mob rau opioid overdoses. FDA yuav tsum txiav txim siab los ntawm Lub Peb Hlis 29 txog seb puas yuav tso cai rau tib neeg mus yuav plaub milligram qhov ntswg yam tsis muaj tshuaj. Lub chaw haujlwm tsis tas yuav tsum lees txais nws cov kws pab tswv yim pom zoo, txawm tias nws feem ntau ua li ntawd.
Emergent BioSolutions tau hais tias Narcan yuav muaj nyob rau hauv khw muag khoom thaum lub caij ntuj sov yog tias FDA pom zoo rau lub hli tom ntej. Lub tuam txhab tseem tsis tau tshaj tawm tias nws yuav raug nqi npaum li cas.
Matt Hartwig, tus kws tshaj lij ntawm lub tuam txhab tau hais tias "Peb tau ua haujlwm ntawm cov phiaj xwm faib khoom nrog cov neeg muaj feem cuam tshuam xws li cov khw muag khoom thiab tsoomfwv cov thawj coj,"
Feem ntau cov xeev twb tau muab daim pam tshuaj uas tso cai rau cov khw muag tshuaj faib Narcan, feem ntau hu ua naloxone, yam tsis muaj tus neeg mob yuav tsum tau nthuav tawm tsab ntawv. Tab sis FDA pom zoo ntawm Narcan rau kev siv hauv khw muag khoom yuav tso cai rau ntau tus neeg kom tau txais kev kho mob yooj yim dua hauv ntau qhov chaw.
"Yog tias naloxone dhau los ua cov khoom tsis yog tshuaj, nws yuav raug muag hauv ntau qhov chaw ua ntej tsis muaj rau cov neeg siv khoom, suav nrog cov tshuab muag khoom, cov khw muag khoom yooj yim, cov khw muag khoom loj thiab cov khw muag khoom loj, ib yam li lwm yam khoom tsis yog tshuaj, "Jody Green, tus thawj coj ntawm FDA cov tshuaj tsis yog tshuaj. faib, hais rau pawg neeg tawm tswv yim hnub Wednesday.
Txij li xyoo 1999, ntau dua 564,000 tus neeg tau tuag los ntawm opioids hauv Teb Chaws Asmeskas hauv peb nthwv dej - thawj zaug los ntawm cov tshuaj opioids, tom qab ntawd los ntawm tus heroin thiab tsis ntev los no los ntawm fentanyl, raws li Lub Chaw Tiv Thaiv thiab Tiv Thaiv Kab Mob. Kev tuag ntau dhau ntawm Opioid tau nce mus txog 17% thaum lub sijhawm muaj kev sib kis los ntawm kwv yees li 69,000 xyoo 2020 txog ze li ntawm 81,000 xyoo 2021.
Thawj Tswj Hwm Trump thawj zaug tshaj tawm tias tus kab mob opioid yog qhov xwm txheej ceev rau pej xeem kev noj qab haus huv hauv 2017. Biden cov thawj coj tau rov hais dua qhov kev tshaj tawm xwm txheej kub ntxhov txhua 90 hnub txij li tus thawj tswj hwm tau ua haujlwm.
"Txhua hnub 187 tus neeg yuav tuag - qhov no yog qhov txaus ntshai heev uas peb xav txog tsis yog tib neeg lawv tus kheej xwb, tab sis tsev neeg, zej zog, chaw ua haujlwm. Qhov no muaj kev cuam tshuam rau tib neeg thiab peb txhua tus raug cuam tshuam los ntawm qhov no, "Manish Vyas, tus lwm thawj coj loj ntawm kev tswj hwm ntawm Narcan maker Emergent BioSolutions, hais rau pawg neeg.
Scott Hadland, tus thawj coj ntawm cov tub ntxhais hluas cov tshuaj ntawm Massachusetts General Tsev Kho Mob, tau hais tias kev nthuav dav ntawm fentanyl mus rau hauv lub tebchaws cov tshuaj tau ua rau muaj kev pheej hmoo ntawm kev noj tshuaj ntau dhau. Ntau tus neeg uas raug fentanyl noj cov tshuaj cuav uas lawv xav tias tau sau tseg tab sis qhov tseeb muaj cov tshuaj muaj zog heev thiab feem ntau tuag taus opioid, Hadland tau hais.
Hadland, uas tau koom nrog Emergent BioSolutions 'kev nthuav qhia, tau hais rau pawg thawj coj hais tias "Thiab ntau ntxiv muaj qhov tshwm sim thib ob uas tseem nce ntxiv," "Peb tab tom pom kev tuag ntau dhau ntawm cov menyuam yaus uas tab tom hla fentanyl hauv cov chaw pej xeem lossis fentanyl uas tej zaum yuav nyob lwm qhov hauv tsev."
Hadland tau hais tias nws qhia cov niam txiv kom khaws Narcan nyob hauv lawv lub tsev thaum muaj xwm txheej ceev. Nws muab piv rau lub tshuab tua hluav taws uas cov tsev neeg yuav tsum muaj rau kev nyab xeeb tab sis cia siab tias yuav tsis tas siv.
Hadland tau hais tias "Hmoov tsis zoo rau cov tub ntxhais hluas feem ntau, tsev neeg thiab cov neeg hauv zej zog thoob plaws lub tebchaws no, txoj kev nkag mus rau tam sim no nyuaj," Hadland tau hais.
Dr. Bobby Mukkamala ntawm American Medical Association tau hais tias Narcan yuav tsum yooj yim kom tau raws li Tylenol los kho mob taub hau lossis decongestant rau qhov ntswg qhov ntswg. Cov tshuaj tsuag qhov ntswg cawm txoj sia yuav tsum yog ib yam hauv cov chaw pej xeem xws li AED cov cuab yeej siv los kho cov neeg mob plawv.
Jessica Hulsey, tus thawj coj ntawm Lub Rooj Sib Tham Txoj Cai Txhaum Cai, tau hais rau pawg thawj coj thaum lub sijhawm hais lus rau pej xeem tias Narcan xav tau tus nqi pheej yig tsis pub tshaj $ 20 ib koob yog tias nws muag ntawm lub txee. Narcan tau ntim raws li ib koob tshuaj thiab nws tuaj yeem siv ntau yam tshuaj kom thim rov qab los ntawm cov tshuaj fentanyl uas muaj zog heev.
Narcan tshem tawm cov tshuaj opioids uas khi rau qhov chaw receptor hauv tib neeg lub paj hlwb. Los ntawm kev tshem tawm thiab thaiv cov tshuaj opioids, cov tshuaj tsuag qhov ntswg tiv thaiv kev tuag ntau dhau los ntawm kev rov qab ua pa nyuaj siab, hais tias Gay Owens, tus thawj coj ntawm kev kho mob thoob ntiaj teb ntawm Emergent BioSolutions.
Tab sis Narcan yuav tsum tau tswj hwm sai li sai tau thaum xav tias muaj kev noj ntau dhau, uas yog vim li cas nws tseem ceeb heev kom paub tseeb tias cov lus qhia rau kev siv cov tshuaj tsuag qhov ntswg yog qhov yooj yim, FDA's Green tau hais.
Hauv kev tshawb fawb txhawb nqa los ntawm Emergent BioSolutions, ntau dua 90% ntawm 71 cov neeg koom tau nkag siab cov lus qhia hauv khw muag khoom thiab siv Narcan ntaus ntawv kom raug thaum simulated overdose thaum muaj xwm ceev siv mannequins. Cov neeg koom nrog suav nrog cov neeg uas muaj ntau theem ntawm kev nyeem ntawv, thiab cov neeg laus thiab cov tub ntxhais hluas.
Tab sis qee tus neeg koom tau tsis meej pem los ntawm tsib kauj ruam cov lus qhia vim tias lawv tau muab faib rau sab thiab sab nraub qaum ntawm lub thawv, hais tias, tus kws muag tshuaj laus ntawm FDA faib uas saib xyuas cov tshuaj tsis raug. Qhov tsis meej pem no tuaj yeem ua rau ncua kev tswj hwm lossis ua yuam kev hauv kev siv Narcan ntaus ntawv kom raug thaum lub sijhawm yog qhov tseem ceeb, raws li Shah.
Cov xwm txheej no tau tshwm sim txawm hais tias cov neeg koom tau tso cai ntau lub sijhawm raws li xav tau kom paub lawv tus kheej nrog Narcan cov lus qhia, uas tej zaum yuav tsis yog qhov xwm txheej hauv ntiaj teb kev noj tshuaj ntau dhau, raws li Shah.
"Yog li ntawd, cov ntaub ntawv khaws tseg tsis ntes qhov kev pheej hmoo siab tshaj plaws siv qhov xwm txheej," Shah hais.
FDA tau tshaj tawm tias Emergent BioSolutions tso tag nrho tsib cov lus qhia nyob rau hauv kev txiav txim nyob rau tom qab ntawm lub thawv thiab tseem suav nrog cov lus qhia hauv cov khoom siv blister pob. Lub tuam txhab tau nthuav tawm qhov kev thuam ntawm lub rooj sib tham tawm tswv yim, tab sis FDA tau hais tias nws tseem tsis tau ntsuas nws.
Tau qhov twg los: https://www.cnbc.com/2023/02/15/opioid-overdose-treatment-narcan-recommended-by-fda-advisors-for-over-the-counter-use-.html