Novavax Hnub Wednesday tau hais tias nws cov tshuaj tiv thaiv tsom rau ob qho tib si Covid-19 thiab tus kab mob khaub thuas ua rau muaj kev tiv thaiv kab mob zoo ib yam li nws cov tshuaj tiv thaiv ib leeg tiv thaiv txhua tus kab mob, hauv qhov kev qhia ntxov tias cov tshuaj tiv thaiv ua ke tsom rau ob tus kab mob tuaj yeem ua pov thawj zoo txawm tias xav tau kev kawm ntxiv.
Tus Thawj Saib Xyuas Kev Kho Mob Filip Dubovsky, thaum hu xov tooj nrog cov neeg sau xov xwm, tau hais tias lub tuam txhab qhov kev sim tshuaj ntsuam xyuas thaum ntxov pom tias muaj txog 25 micrograms ntawm Covid formulation ua ke nrog txog li 35 micrograms ntawm tus kab mob khaub thuas ua rau muaj kev cia siab ntawm cov tshuaj tiv thaiv kab mob.
"Dab tsi peb tau pom nyob rau hauv txoj kev tshawb no yog peb muaj peev xwm tau txais cov lus teb tiv thaiv kab mob tiag tiag piv rau cov tshuaj tiv thaiv tus kheej ua ntej ua ke," Dubovsky tau hais.
Cov neeg koom nrog theem ib sim muaj hnub nyoog nruab nrab ntawm 59 thiab lawv txhua tus tau txais cov tshuaj tiv thaiv Covid yav dhau los. Novavax tab tom nthuav tawm cov ntaub ntawv ntawm World Vaccine Congress hauv Washington, DC, hnub Wednesday.
Novavax npaj mus rau pem hauv ntej nrog rau theem ob mus sib hais xyoo no kom paub meej txog qib kev noj tshuaj uas tsim nyog, thiab pib ib theem peb sim ntawm kev ua tau zoo thaum lub caij khaub thuas xyoo 2023 thaum ntxov, Dubovsky tau hais.
Cov kws paub txog kev noj qab haus huv pej xeem cia siab tias Covidien kom dhau los ua tus kab mob ua pa raws caij nyoog zoo ib yam li tus mob khaub thuas uas yuav xav tau txhaj tshuaj tiv thaiv txhua xyoo vim tias kev tiv thaiv kev tiv thaiv los ntawm kev txhaj tshuaj tsis dhau sijhawm. Cov neeg tsim tshuaj tiv thaiv tab tom sib tw los tsim kev txhaj tshuaj sib xyaw ua ke txhawm rau txhawm rau txhawm rau txhawm rau ua kom yooj yim rau tib neeg kom tau txais kev tiv thaiv thaum Covid thiab mob khaub thuas sib kis ib txhij.
Dubovsky tau hais tias "Cov tshuaj tiv thaiv kev sib xyaw ua ke yog kev cuam tshuam kev noj qab haus huv rau pej xeem txaus nyiam," "Koj tab tom ntaus ob kab mob uas ua rau muaj kev phom sij rau lub neej hauv ib qho kev sib cuag kho mob, muab tshuaj tiv thaiv ib zaug."
Novavax, tus neeg koom nrog thaum ntxov hauv tsoomfwv Meskas cov kev sib tw xyoo 2020 los tsim cov tshuaj tiv thaiv Covid, tam sim no tsis muaj cov tshuaj tiv thaiv kev tso cai hauv Asmeskas Lub tuam txhab thov kom Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj tso cai rau nws cov tshuaj tiv thaiv Covid thaum Lub Ib Hlis. Dubovsky hais rau cov neeg sau xov xwm rau hnub Wednesday tias FDA tseem tab tom tshuaj xyuas Novavax daim ntawv thov.
Novavax's Covid tshuaj tiv thaiv siv cov cuab yeej sib txawv dua li Pfizer's thiab Niaj hnubCov kev txhaj tshuaj, uas tso siab rau tus xa xov RNA los hloov tib neeg lub hlwb mus rau hauv cov chaw tsim khoom uas tsim cov ntawv luam ntawm tus kab mob kis kab mob protein, ua rau muaj kev tiv thaiv kab mob uas tiv thaiv Covid. Tus kab mob yog ib feem ntawm tus kab mob uas latches mus rau thiab invades tib neeg hlwb.
Novavax qhov kev txhaj tshuaj, ntawm qhov tod tes, ua kom tag nrho cov kab mob sib kis sab nraud ntawm tib neeg lub cev. Cov kab mob caj ces rau cov kab mob loj yog muab tso rau hauv ib qho kab mob baculovirus uas kis kab mob, uas tom qab ntawd tsim cov ntawv luam ntawm cov kab laug sab uas tau ntxuav thiab muab rho tawm. Daim ntawv luam tawm, uas tsis tuaj yeem rov ua dua lossis ua rau Covid, tau txhaj rau tib neeg los txhawb kev tiv thaiv kab mob tiv thaiv tus kabmob.
Cov tshuaj tiv thaiv kuj tseem siv cov tshuaj adjuvant uas muaj cov tshuaj purified los ntawm cov tawv ntoo hauv South America, los txhawb kev tiv thaiv kab mob. Cov tshuaj adjuvant tau siv rau hauv cov tshuaj tiv thaiv kab mob malaria thiab shingles. Novavax's stand-alone Covid txhaj tshuaj muaj 5 micrograms ntawm daim ntawv dav dav thiab 50 micrograms ntawm adjuvant.
Novavax siv tib lub thev naus laus zis rau nws tus neeg sib tw tshuaj tiv thaiv kab mob khaub thuas ib leeg, uas yog tsom rau plaub hom kab mob.
Thaum txog li 25 microgram Covid tsim nyob rau hauv cov tshuaj tiv thaiv ua ke yog siab dua qhov kev txhaj tshuaj ib leeg, Dubovsky tau hais tias nws zoo nyob rau hauv thaj tsam ntawm lwm cov tshuaj tiv thaiv FDA tso cai, uas muaj qib ntawm 50 thiab 100 micrograms.
Lub 25 microgram formulation tau sim nyob rau hauv kev sim tshuaj tiv thaiv ua ke tau txais txiaj ntsig zoo thiab nyab xeeb, Dubovsky tau hais. Cov kev mob tshwm sim feem ntau yog qhov mob ntawm qhov chaw txhaj tshuaj, qaug zog thiab mob taub hau, nws hais.
Tau qhov twg los: https://www.cnbc.com/2022/04/20/novavax-says-vaccine-targeting-covid-and-flu-shows-promising-results-in-early-data.html