Cov khoom xyaw ntuj tsim nyob rau hauv cov tshuaj pleev ib ce tuaj yeem hloov nrog cov khoom lag luam ruaj khov … [+]
Stable Diffusion generative algorithm.
Koj qhov kev tu tawv nqaij niaj hnub yuav xav tau kev hloov kho tshiab - tab sis tsis yog vim koj laus dua. Cov khoom xyaw nquag siv hauv tshuaj pleev ib ce yuav zoo rau koj cov tawv nqaij tab sis tsis yog rau lub ntiaj teb. Feem ntau ntawm lawv yog los ntawm cov nroj tsuag tsis tshua muaj lossis cov tsiaj tsis tshua muaj siab. Piv txwv li, squalene, ib yam khoom muaj nyob rau hauv cream thiab serums, yog sau los ntawm shark daim siab. Qhov ntawd nthuav tawm qhov teeb meem - thiab tsis yog rau cov tsiaj uas muaj kev puas tsuaj xwb, tab sis rau cov khoom lag luam kev ruaj ntseg, tswj cov nqi, thiab ua kom ntseeg tau qhov zoo ib yam ntawm cov khoom xyaw.
Skincare yog ib 100-billion-duas lag luam. Tsis muaj qhov xav tsis thoob cov tuam txhab biotechnology tshiab tab tom txav mus rau hauv qhov haujlwm no. Qhov lawv tab tom nqa tuaj rau lub rooj yog huv dua thiab ntsuab dua rau cov khoom uas peb twb siv lawm. Es tsis txhob raug sau los ntawm cov nroj tsuag qus, cov khoom xyaw tseem ceeb uas siv rau hauv cov tshuaj pleev ib ce tuaj yeem tsim los ntawm cov qoob loo cog qoob loo, zoo li cov qab zib, siv cov fermentation precision. Cov thev naus laus zis no muaj peev xwm tsim cov enzymes ntshiab, cov vitamins, tshuaj tsw qab, cov xim ntuj, thiab cov molecules active nyob rau hauv ib puag ncig tswj ntawm ib feem ntawm tus nqi.
Bio-raws li cov khoom siv tawv nqaij twb muaj nyob rau hauv kev ua lag luam. Biossance, uas yog tus tswv Amyris
"Biotechnology ua rau peb nthuav dav cov khoom xyaw palette ntawm kev lag luam kev zoo nkauj rau cov molecules hauv txhua qhov chaw ntawm tsob ntoo ntawm lub neej, kev ncaj ncees thiab ruaj khov," Jasmina hais. "Ntawm Arcaea, peb pom yuav ua li cas cov no tuaj yeem siv rau hauv txoj hauv kev muaj zog hauv kev zoo nkauj los tsim cov pawg tshiab ntawm cov khoom xyaw thiab cov khoom ua haujlwm."
Tseeb tiag, biotechnology innovation tuaj yeem dhau los hloov cov khoom xyaw uas twb muaj lawm thiab pab qhia cov khoom tshiab uas zoo dua li qhov tam sim no ntawm peb lub txee. Ib lub tuam txhab biotech tshiab hu ua Sestina Bio yog mus tom qab cov khoom xyaw tshwj xeeb. Lawv thawj lub hom phiaj ua lag luam yog bakuchiol, ib qho kev hloov pauv ntuj retinol uas tsis ua rau UV rhiab heev thiab khaus khaus uas retinol tuaj yeem ua tau. Lub downside ntawm kev siv no super-molecule yog tias bakuchiol yog tam sim no los ntawm cov nroj tsuag hem, yog li nws cov saw hlau tsis muaj peev xwm hloov tau - thiab tus nqi nce nrog qhov xav tau. Sestina tau tsim tawm los tsim cov khoom muaj txiaj ntsig no siv hluavtaws biology thiab precision fermentation.
Tab sis kev tsim cov txheej txheem biomanufacturing tshiab tsis yog ib qho yooj yim feat: ua ntej, koj yuav tsum paub yuav ua li cas ua kom cov khoom ntawd nyob rau hauv ib tug kab mob xws li poov xab, ces engineer ib hom uas muaj peev xwm ua lag luam kom muaj nuj nqis ntawm nws thiab muaj zog txaus kom loj hlob nyob rau hauv industrial tej yam kev mob. ua ntej koj yuav scale li ntau lawm. Cov txheej txheem no feem ntau siv sijhawm ntau xyoo. Tab sis Sestina muaj peev xwm tsim tau ib tug npaj-rau-scale-up strain nyob rau hauv tsawg dua 12 lub hlis. Qhov no yog lub sijhawm tsis tau muaj dhau los rau kev tsim khoom tshiab hauv kev lag luam biotech. Lawv muaj peev xwm tuav tau ib lub xyoo los ntawm kev siv cov ntaub ntawv tshawb fawb thiab cov cuab yeej siv tshuab genome, xws li Inscripta's Onyx® platform.
Rau cov tuam txhab xws li Sestina, Inscripta tab tom txhim kho cov txheej txheem kev lag luam nrog lawv cov cuab yeej Onyx uas ua CRISPR kho thiab ntau ntxiv hauv lub thawv dub. Txoj kev nws ua haujlwm yog tias koj muab tso rau hauv cov txheej txheem poov xab thiab tom qab 2-4 hnub nws rov qab ntau txhiab lub hlwb uas tuaj yeem kuaj xyuas kev txhim kho. Suab zoo li khawv koob? Tsis yog. Nws yog qhov ua ke ntawm bioinformatics software, microfluidics siab heev, kev cai chemistry, optimized enzymes, thiab kev suav lub zog uas ua rau lub tshuab no ua txhua yam uas cov neeg ua haujlwm puv npo tuaj yeem ua tau - tab sis sai dua. Nrog nws, tej yaam num uas tau siv ntau xyoo tam sim no tuaj yeem ua tiav hauv ob peb lub hlis xwb, thiab Sestina's bakuchiol zaj dab neeg ua tau zoo ua pov thawj nws.
"Tsim Bakuchiol strain uas muaj peev xwm ciaj sia nyob rau hauv kev nruj ntawm scaleup thiab yeej nyob rau hauv kev tsim khoom yuav tsum tau txhim kho enzyme tseem ceeb thiab npaj txhij txog tag nrho cov genome edits uas txhawb txoj kev. Lub Onyx tau tso cai rau peb ua kom tiav ob lub hom phiaj ua ke, ua kom nrawm nrawm rau peb cov txheej txheem tag nrho, "said Andrew Horwitz, VP ntawm R&D ntawm Sestina Bio, hauv ib tshaj tawm.
Bakuchiol yog ib qho ntawm thawj cov khoom lag luam bioproduct uas tau tsim nrog kev pab los ntawm Onyx platform. Tab sis lwm cov tuam txhab hluavtaws biology ua haujlwm hauv cov khoom xyaw qhov chaw tseem tab tom nrhiav kom ceev lawv cov txheej txheem tsim khoom nrog Inscripta's Onyx ntsuas. Cov uas siv Inscripta thev naus laus zis suav nrog cov neeg loj heev nyiam Amyris, Ginkgo Bioworks Cov, Thiab Willow Biosciences. Willow Biosciences tab tom ua haujlwm los tsim cov khoom xyaw uas muaj siab dawb huv rau kev saib xyuas tus kheej, zaub mov thiab dej haus, thiab cov khw muag tshuaj, xws li cannabigerol ("CBG"), thawj cov khoom lag luam hauv nws cov ntaub ntawv.
Inscripta nws tus kheej tsis yog mus tom qab cov khoom xyaw tshwj xeeb tab sis theej muab cov cuab yeej rau cov tuam txhab hluavtaws biology kom ncav cuag lawv cov hom phiaj sai dua los ntawm kev ua kom cov kev tshawb fawb, tsim, thiab kev tsim cov khoom lag luam tshiab. Ginkgo Bioworks kuj tseem ua haujlwm strain raws li kev pabcuam: lawv tau ua haujlwm nrog cov tuam txhab nyiam Givaudan thiab Bolt xov los pab hloov cov khoom xyaw ntuj rau hauv ntau cov qauv tsim nyob rau hauv microbes.
Hauv kev nkag siab, cov tuam txhab zoo li Inscripta thiab Ginkgo ua yog muab cov lus pov thawj "xaiv thiab shovels" rau cov khoom xyaw ruaj khov ua lag luam goldrush. Lawv cov thev naus laus zis tuaj yeem pab txo cov khoom lag luam lub sijhawm los ntawm xyoo mus rau lub hlis thiab qhov ntawd muab qhov kev sib tw tiag tiag hauv ib puag ncig biotech ceev ceev. Qhov ntawd txhais tau li cas rau cov tuam txhab yog lawv tuaj yeem nqa cov khoom xyaw kom ruaj khov rau kev lag luam sai dua - thiab rau peb, uas peb tuaj yeem muab lawv tso rau ntawm peb lub ntsej muag sai dua hauv kev sib tw nrog lub sijhawm.
Ua tsaug rau koj Katia Tarasava rau kev tshawb fawb ntxiv thiab qhia txog kab lus no. Kuv yog tus tsim ntawm SynBioBeta, thiab qee lub tuam txhab uas kuv sau txog, suav nrog Inscripta, Amyris, thiab Ginkgo Bioworks, yog tus txhawb nqa ntawm Rooj sablaj SynBioBeta thiab limtiam zom.
Tau qhov twg los: https://www.forbes.com/sites/johncumbers/2022/11/26/how-the-skincare-industry-is-turning-to-gene-editing-in-a-race-against-time/