Tojsiab
Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj rau hnub Friday tau tshaj tawm tsab ntawv tso cai siv thaum muaj xwm txheej ceev rau kev kho mob monoclonal antibody tshiab uas tus kws tsim tshuaj Eli Lilly hais tias ua haujlwm tawm tsam tus kabmob coronavirus 'omicron variant, tejzaum nws tso cov hniav nyob rau lub hlis ntawm kev tsis txaus txaus rau kev kho Covid-19.
Eli Lilly thiab tuam txhab lub tsev hauv paus hauv Alcobendas, Madrid, Spain.
Cristina Arias /Cover / Getty Images
Cov Lus Tseem Ceeb
FDA tso cai rau kev kho mob - hu ua bebtelovimab - los kho mob me mus rau nruab nrab Covid-19 hauv qee cov neeg 12 xyoo thiab laus dua uas muaj kev pheej hmoo siab ntawm cov tsos mob hnyav thiab rau cov kev kho mob lwm yam tsis tuaj yeem siv tau lossis kho mob tsim nyog.
Hnub Thursday, Eli Lilly tau tshaj tawm tias nws tau pom zoo xa mus txog 600,000 koob tshuaj bebtelovimab rau tsoomfwv Meskas los ntawm Lub Peb Hlis 31 rau tsawg kawg yog $ 720 lab, nrog rau kev xaiv xa 500,000 koob ntxiv los ntawm Lub Xya Hli 31.
Kev sim tshuaj xyuas tau pom tias bebtelovimab pab daws qee cov neeg mob cov tsos mob sai dua thiab txo qis tus kab mob hauv lawv lub cev tom qab tsib hnub, FDA tau tshaj tawm.
Txawm li cas los xij, bebtelovimab lub peev xwm los tiv thaiv Covid-19 cov tsos mob hnyav tseem tsis tau sim, qhov New York Times qhia.
Tus Keeb Kwm Tseem Ceeb
Kev kho mob monoclonal antibody pab tiv thaiv kab mob coronavirus los ntawm kev txhawb nqa lub cev lub cev tiv thaiv kab mob. Ntau qhov kev kho mob no tsom rau tus kab mob cov kab mob sib kis, txwv tsis pub tus kab mob rov ua dua tshiab. Txawm li cas los xij, kev hloov pauv mus rau omicron variant's spike protein ntau tau siv ntau txoj kev kho mob monoclonal antibody - suav nrog ob qho kev kho Eli Lilly ua ntej - tsis muaj txiaj ntsig. Tau ob peb lub lis piam, ib qho tshuaj los ntawm GlaxoSmithKline thiab Vir Biotechnology yog tib txoj kev kho mob monoclonal antibody uas tseem muaj txiaj ntsig tiv thaiv omicron variant, thiab nyob rau lub hli tsis ntev los no qee lub tsev kho mob tau tshaj tawm cov khoom siv tshuaj tiv thaiv monoclonal tsawg. Lub hli tas los, FDA tau tshem tawm nws qhov kev tso cai ntawm bamlanivimab thiab etesevimab, txawm hais tias ntau lub tsev kho mob tau yeem tso tseg tsis pub faib nws. Txawm li cas los xij, lub tuam txhab txhawb nqa kev sim kuaj pom pom Eli Lilly cov tshuaj tshiab tseem ua haujlwm tawm tsam omicron, suav nrog BA.2 omicron subvariant. Cov tshuaj tshiab thiab tshuaj tiv thaiv Covid los ntawm Pfizer thiab Merck tuaj yeem pab txo qis kev kho mob.
Tsis meej
Bebtelovimab tau tshawb pom los ntawm Vancouver-based biotechnology tuam txhab AbCellera, uas tau tshuaj xyuas cov tshuaj tiv thaiv kab mob los ntawm cov neeg uas tau zoo los ntawm Covid-19 kom pom qhov twg zoo tshaj plaws tiv thaiv tus kab mob. AbCellera tau muab cov tshuaj tiv thaiv zoo tshaj plaws - suav nrog bebtelovimab - rau Eli Lilly, uas yog lub luag haujlwm rau kev tsim, tsim khoom thiab faib lawv. Vim tias bebtelovimab tsom mus rau qhov tsis tshua muaj kev hloov pauv ntawm cov protein ntau, nws tuaj yeem ua haujlwm ntxiv rau yav tom ntej, AbCellera tau hais.
Kev Nkag Siab Hais
"Qhov kev tso cai no yog ib kauj ruam tseem ceeb hauv kev ua kom tau raws li qhov xav tau ntawm cov cuab yeej siv ntau dua los kho cov neeg mob raws li qhov hloov pauv tshiab ntawm tus kab mob txuas ntxiv mus," said Dr. Patrizia Cavazzoni, tus thawj coj ntawm FDA's Center for Drug Evaluation and Research.
Contra
Bebtelovimab tsis tau tso cai rau cov neeg mob pw hauv tsev kho mob vim Covid-19 lossis xav tau kev kho cov pa oxygen vim tus kab mob, FDA tau hais. Monoclonal cov tshuaj tiv thaiv zoo li bebtelovimab tuaj yeem cuam tshuam nrog cov txiaj ntsig tsis zoo thaum muab rau cov neeg mob Covid hauv tsev kho mob xav tau cov pa oxygen siab lossis tshuab ua pa, lub chaw haujlwm tau hais.
ntxiv nyeem ntawv
"Tebchaws Asmeskas Pauses Kev Tshaj Tawm Ntawm Kev Kho Mob Monoclonal Antibody Ua pov thawj tias tsis muaj txiaj ntsig tiv thaiv Omicron" (Forbes)
Tau qhov twg los: https://www.forbes.com/sites/zacharysmith/2022/02/11/fda-authorizes-eli-lilly-antibody-treatment-that-fights-omicron/