CDC vaj huam sib luag pom zoo tshuaj tiv thaiv Novavax rau cov neeg laus

Lub Chaw Tiv Thaiv Kab Mob thiab Tiv Thaiv Cov Kws Pab Tswv Yim ywj pheej pom zoo NovavaxOb koob tshuaj tiv thaiv Covid-19 yog thawj koob rau cov neeg laus hnub Tuesday, ib qho ntawm cov kauj ruam kawg ua ntej cov khw muag tshuaj tuaj yeem pib txhaj tshuaj.

Pawg CDC tau pom zoo ib qho kev pom zoo rau cov tshuaj tiv thaiv rau cov neeg muaj hnub nyoog 18 xyoo thiab laus dua tom qab tshuaj xyuas qhov kev txhaj tshuaj tiv thaiv kev nyab xeeb thiab ua haujlwm tau zoo thaum lub sijhawm sib tham rau pej xeem hnub Tuesday. CDC Tus Thawj Coj Dr. Rochelle Walensky tuaj yeem muab lub teeb ntsuab rau kev txhaj tshuaj tiv thaiv pib sai li sai tau lub lim tiam no.

Novavax Tshuag tau nce 12% tom qab CDC vaj huam sib luag pom zoo.

Walensky qhov kev pom zoo yuav ua tiav ob xyoos taug kev rau Novavax, yog ib tus neeg koom nrog thaum ntxov hauv Asmeskas kev sib tw los tsim cov tshuaj tiv thaiv los tiv thaiv Covid-19. Lub tuam txhab me me Maryland biotech tau txais $ 1.8 nphom ntawm cov neeg them se nyiaj los ntawm Kev Ua Haujlwm Warp Ceev, tab sis tau tawm tsam kom tau txais nws lub hauv paus tsim khoom thiab thaum kawg poob qab Pfizer thiab Moderna.

Novavax cov tshuaj tiv thaiv yuav nkag mus rau Tebchaws Meskas thaum lub sijhawm ntau tshaj peb-plaub ntawm Asmeskas cov neeg laus, 77%, tam sim no tau txhaj tshuaj tiv thaiv tag nrho nrog Pfizer, Moderna thiab tsawg dua li Johnson & Johnson txhaj tshuaj, raws li CDC cov ntaub ntawv.

Asmeskas cov kws saib xyuas kev noj qab haus huv thiab cov thawj coj Novavax tau hais tias cov tshuaj tiv thaiv yuav muab lwm txoj hauv kev rau cov neeg uas tsis xav txhaj tshuaj Pfizer thiab Moderna. Txhua qhov chaw ntawm 26 lab txog 37 lab tus neeg laus tseem tsis tau txhaj tshuaj tiv thaiv hauv Asmeskas, raws li CDC cov ntaub ntawv, tab sis nws tsis paub meej tias pes tsawg tus neeg yuav xaiv txhaj tshuaj Novavax.

Biden tus thawj coj tau ruaj ntseg 3.2 lab koob tshuaj Novavax cov tshuaj tiv thaiv txog tam sim no, raws li Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tib Neeg.

"Lub hom phiaj tseem ceeb ntawm cov pej xeem rau Novavax yuav yog 10% txog 13% ntawm cov uas tsis tau txhaj tshuaj," hais tias Dr. Oliver Brooks, ib tug tswv cuab thiab tus thawj kws kho mob ntawm Watts HealthCare Corporation hauv Los Angeles hais.

Brooks tau hais tias "Kuv nkag siab tias peb tau tsom mus rau cov pej xeem ntawd nrog kev cia siab tias tej zaum cov tshuaj tiv thaiv kab mob no yuav hloov lawv los ntawm kev txhaj tshuaj tiv thaiv tsis tau txhaj tshuaj tiv thaiv," Brooks tau hais.

Novavax txhaj tshuaj tau 90% zoo ntawm kev tiv thaiv kab mob tag nrho thiab 100% zoo ntawm kev tiv thaiv kab mob hnyav thaum cov alpha variant ntawm Covid yog qhov tseem ceeb, raws li cov ntaub ntawv soj ntsuam. Lub tuam txhab tsis tau tshaj tawm cov ntaub ntawv ntawm qhov ua tau zoo ntawm lub ntiaj teb ntawm nws cov tshuaj tiv thaiv omicron thiab nws cov subvariants.

Tab sis Novavax cov tshuaj tiv thaiv zoo li tsim cov tshuaj tiv thaiv kab mob tiv thaiv omicron thiab nws cov subvariants, uas yuav qhia tau tias nws muaj txiaj ntsig zoo rau qhov sib txawv. Lub tuam txhab cov ntaub ntawv tiv thaiv kab mob tiv thaiv omicron tau qhuas cov tswv cuab ntawm Pawg Saib Xyuas Khoom Noj thiab Tshuaj Tshuaj Tiv Thaiv lub hli tas los.

FDA hauv daim ntawv qhia tseeb rau cov kws kho mob ceeb toom tias Novavax cov tshuaj tiv thaiv zoo li ua rau muaj kev pheej hmoo mob plawv hu ua myocarditis. FDA cov tub ceev xwm tau tshaj tawm plaub tus neeg mob myocarditis thiab pericarditis - o hauv daim nyias nyias nyob ib puag ncig lub plawv - los ntawm Novavax qhov kev sim tshuaj rau cov txiv neej hluas hnub nyoog 16 txog 28 xyoo.

Pfizer thiab Moderna txhaj tshuaj kuj ua rau muaj kev pheej hmoo siab ntawm myocarditis rau cov tub hluas thiab cov tub hluas tom qab koob thib ob. CDC tau pom tias Covid kis muaj feem yuav mob plawv ntau dua li kev txhaj tshuaj nrog Pfizer lossis Moderna txhaj tshuaj. Myocarditis feem ntau tshwm sim los ntawm kev kis kab mob.

Novavax cov tshuaj tiv thaiv siv lub platform sib txawv dua li Pfizer's thiab Moderna txhaj tshuaj. Cov tshuaj tiv thaiv Novavax yog raws li cov cuab yeej siv protein uas twb tau siv rau hauv cov tshuaj tiv thaiv kab mob HPV thiab kab mob siab B.

Lub tuam txhab tsim cov ntawv luam ntawm tus kab mob spike protein uas tsis muaj zog los ntawm kev tso cov kab mob caj ces rau hauv kab kab mob uas kis kab mob npaws. Cov ntawv luam theej tawm tau raug sau thiab ua kom huv ntawm cov hlwb rau nws cov tshuaj tiv thaiv.

Spike protein yog cov txheej txheem uas tus kab mob siv los cuam tshuam tib neeg lub hlwb. Cov ntawv luam tawm hauv cov tshuaj tiv thaiv npaj lub cev tiv thaiv kab mob los tsim cov tshuaj tiv thaiv kab mob uas thaiv tus kab mob los ntawm kev ua phem rau tib neeg lub hlwb. Novavax cov tshuaj tiv thaiv kuj tseem muaj cov khoom xyaw ntxiv, hu ua adjuvant, uas yog muab los ntawm cov tawv ntoo ntawm South American ntoo los tsim lub cev tiv thaiv kab mob ntau dua los tiv thaiv tus kabmob.

Pfizer thiab Moderna cov tshuaj tiv thaiv, los ntawm qhov sib txawv, siv tus xa xov RNA thev naus laus zis. Lawv cov kev txhaj tshuaj xa xa xov RNA rau tib neeg lub hlwb, uas tom qab ntawd tsim cov ntawv luam ntawm cov protein tsis muaj zog los tsim cov tshuaj tiv thaiv kab mob los tua tus kab mob. Pfizer thiab Moderna txhaj tshuaj yog thawj cov tshuaj tiv thaiv mRNA tau txais kev pom zoo los ntawm FDA.

Novavax cov kev txhaj tshuaj kuj tseem khaws cia ntawm lub tub yees txias, thaum Pfizer's thiab Moderna txhaj tshuaj yuav tsum tau txias txias.

Txawm hais tias FDA tau tso cai ntau zaus rau Pfizer's thiab Moderna txhaj tshuaj raws li cov tshuaj tiv thaiv zoo thiab muaj txiaj ntsig zoo rau txhua pab pawg hnub nyoog hauv Asmeskas, cov neeg saib xyuas kev noj qab haus huv tau tawm tsam kom ntseeg ntau lab tus neeg tsis ntseeg los txhaj tshuaj.

Teb Chaws Asmeskas tab tom npaj yuav hloov cov tshuaj tiv thaiv txhawm rau txhawm rau txhawm rau kis tau ntau dua BA.4 lossis BA.5 omicron subvariants, uas tam sim no tseem ceeb, ua ntej ntawm qhov kev npaj tshuaj tiv thaiv lub caij nplooj zeeg. Cov tshuaj tiv thaiv Covid tsis tshua muaj txiaj ntsig ntawm kev tiv thaiv kev kis kab mob los ntawm omicron vim qhov sib txawv ntawm ntau qhov kev hloov pauv, tab sis lawv feem ntau tseem tiv thaiv kab mob hnyav.

Tsoomfwv Meskas cov kws saib xyuas kev noj qab haus huv ntseeg tias hloov pauv cov qauv tshuaj tiv thaiv rau lub hom phiaj omicron sib txawv nrog rau cov kab mob thawj zaug uas tshwm sim hauv Wuhan, Tuam Tshoj xyoo 2019 yuav muab kev tiv thaiv ntau dua tiv thaiv tus kab mob lub caij nplooj zeeg no.

Novavax cov tshuaj tiv thaiv, zoo li txhua qhov kev tso cai Covid tam sim no txhaj tshuaj, yog raws li tus kab mob thawj zaug uas tshwm sim hauv Suav teb. Zoo li Pfizer thiab Moderna, Novavax tab tom tsim cov tshuaj tiv thaiv uas tsom rau qhov sib txawv ntawm omicron, tab sis cov thawj coj hauv tuam txhab tau hais tias nws tsis paub meej tias lawv yuav tsum tau dov tawm qhov kev txhaj tshuaj tshiab vim tias lub tuam txhab cov tshuaj tiv thaiv tam sim no ua rau muaj kev tiv thaiv kab mob dav dav rau qhov sib txawv.

CDC thiab FDA tsis tau pom zoo sib xyaw thiab sib piv Novavax cov tshuaj tiv thaiv nrog Pfizer's thiab Moderna txhaj tshuaj raws li kev txhawb nqa. Novavax tau hais tias nws npaj yuav thov FDA tso cai txhaj tshuaj tiv thaiv nws cov tshuaj tiv thaiv.